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This one supports the notion that the progression of the volume load throughout the training period influences muscular adaptations to resistance training, even more so than the accumulated volume load, at least in untrained individuals.
LWWMuscle Hypertrophy Is Affected by Volume Load Progression... : The Journal of Strength & Conditioning Researchion zone (RM Zone) progression model carried out to muscle failure on volume load progression (VLPro), muscle strength, and cross-sectional area (CSA). The sample comprised 24 untrained men separated in 2 groups: %1RM (n = 14) and RM Zone (n = 10). Muscle CSA and muscle strength (1RM) were assessed before and after 24 training sessions, and an analysis of covariance was used. Volume load progression and accumulated VL (VLAccu) were compared between groups. The relationships between VLProg, VLAccu, 1RM, and CSA increases were also investigated. A significance level of p ≤ 0.05 was adopted for all statistical procedures. Volume load progression was greater for RM Zone compared with %1RM (2.30 ± 0.58% per session vs. 1.01 ± 0.55% per session; p < 0.05). Significant relationships were found between 1RM and VLProg (p < 0.05) and CSA and VLProg (p < 0.05). No between-group differences were found for VLAccu (p > 0.05). Analysis of covariance revealed no between-group differences for 1RM absolute (p < 0.05) or relative changes (p < 0.05). However, post hoc testing revealed greater absolute and relative changes in CSA for the RM Zone group compared with the %1RM group (p < 0.001). In conclusion, RM Zone resulted in a greater VLPro rate and muscle CSA gains compared with %1RM, with no differences in VLAccu and muscle strength gains between progression models....
Collectively, these results suggest that the progression of the volume load affects muscle hypertrophy, even more so than the accumulated volume load, while supporting that training in a specific repetition zone may be a better option when training to failure.